1.Schizophrenia
2.Severe depression
3.Anxiety
4.Obsessive thoughts
Interactions for Paliperidone
1.Increased risk of antipsychotic-related extrapyramidal symptoms when used with central acetylcholinesterase inhibitors.
2.May reduce the therapeutic effect of anti-Parkinson`s agents (dopamine agonist).
3.Serum levels may be reduced by carbamazepine.
4.Concurrent use may increase toxicity of other CNS depressants.
5.Serum levels may be increased by itraconazole.
6.Lithium may increase neurotoxic effects of paliperidone.
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